The top 10 medications by number of monthly prescriptions in United States
(Data released from April 2014 through March 2015):
1. Synthroid (levothyroxine), 21.5 million
2. Crestor (rosuvastatin), 21.4 million
3. Ventolin HFA (albuterol), 18.2 million
4. Nexium (esomeprazole), 15.2 million
5. Advair Diskus (fluticasone), 13.7 million
6. Lantus Solostar (insulin glargine), 10.9 million
7. Vyvanse (lisdexamfetamine), 10.4 million
8. Lyrica (pregabalin), 10.0 million
9. Spiriva Handihaler (tiotropium), 9.6 million
10. Januvia (sitagliptin), 9.1 million
Source:
http://www.webmd.com/news/20150508/most-prescribed-top-selling-drugs
Top 100 Prescriptions, Sales (100 Best-Selling)
| Drug Name | Sales |
| Synthroid | 21,561,481 |
| Crestor | 21,478,776 |
| Ventolin HFA | 18,203,939 |
| Nexium | 15,298,228 |
| Advair Diskus | 13,776,325 |
| Lantus Solostar | 10,939,840 |
| Vyvanse | 10,413,999 |
| Lyrica | 10,022,365 |
| Spiriva Handihaler | 9,635,935 |
| Januvia | 9,148,946 |
| Lantus | 9,145,153 |
| Abilify | 9,099,978 |
| Symbicort | 8,265,594 |
| Tamiflu | 8,025,275 |
| Cialis | 7,472,719 |
| Viagra | 7,104,074 |
| Suboxone | 6,985,631 |
| Zetia | 6,925,137 |
| Xarelto | 6,739,752 |
| Bystolic | 6,461,435 |
| Celebrex | 6,449,730 |
| Nasonex | 6,432,382 |
| Namenda | 5,961,360 |
| Flovent HFA | 5,736,650 |
| Oxycontin | 5,347,532 |
| Diovan | 5,224,025 |
| Thyroid | 5,128,576 |
| Voltaren Gel | 5,123,676 |
| Nuvaring | 4,917,514 |
| Afluria | 4,650,167 |
| Dexilant | 4,620,902 |
| Benicar | 4,483,555 |
| Proventil HFA | 4,385,623 |
| Humalog | 4,209,193 |
| Novolog Flexpen | 4,179,914 |
| Novolog | 3,968,615 |
| Vesicare | 3,686,182 |
| Premarin | 3,462,987 |
| Benicar HCT | 3,352,383 |
| Lo Loestrin Fe | 3,335,659 |
| Lumigan | 3,298,208 |
| Namenda XR | 3,157,234 |
| Humalog Kwikpen | 3,043,015 |
| Janumet | 3,027,293 |
| Pataday | 2,905,818 |
| Ortho-Tri-Cy Lo 28 | 2,900,301 |
| Travatan Z | 2,861,717 |
| Combivent Respimat | 2,846,891 |
| Toprol-XL | 2,811,156 |
| Pristiq | 2,769,837 |
| Invokana | 2,711,901 |
| Minastrin 24 Fe | 2,555,803 |
| Strattera | 2,418,649 |
| Seroquel XR | 2,390,205 |
| Vytorin | 2,384,517 |
| Focalin XR | 2,334,004 |
| Dulera | 2,307,692 |
| Levemir Flexpen | 2,283,328 |
| Zostavax | 2,279,662 |
| Avodart | 2,271,799 |
| Pradaxa | 2,257,507 |
| Chantix | 2,208,377 |
| Eliquis | 2,179,340 |
| Humira | 2,173,082 |
| Levemir Flextouch | 2,164,191 |
| Levemir | 2,100,856 |
| Victoza 3-Pak | 2,078,630 |
| Combigan | 1,909,750 |
| Exelon | 1,825,705 |
| Tradjenta | 1,744,708 |
| Premarin Vaginal | 1,738,728 |
| Enbrel | 1,691,819 |
| Onglyza | 1,691,615 |
| Ranexa | 1,661,050 |
| Truvada | 1,651,083 |
| Welchol | 1,644,996 |
| Linzess | 1,639,652 |
| Latuda | 1,635,230 |
| Alphagan P | 1,483,322 |
| Viibryd | 1,425,156 |
| Effient | 1,406,934 |
| Norvir | 1,376,523 |
| Amitiza | 1,371,937 |
| Azor | 1,338,802 |
| Advair HFA | 1,310,993 |
| Uloric | 1,293,249 |
| Lotemax | 1,245,330 |
| Myrbetriq | 1,230,040 |
| Asmanex Twisthaler | 1,219,923 |
| Epiduo | 1,212,887 |
| Xopenex HFA | 1,204,025 |
| Durezol | 1,189,206 |
| Patanol | 1,181,134 |
| Atripla | 1,147,295 |
| Aggrenox | 1,144,739 |
| Exforge | 1,134,532 |
| Humulin R | 1,110,123 |
| Carafate | 1,110,008 |
| Novolog Flxpen Mix 70/30 | 1,069,219 |
| Relpax | 1,035,265 |
| Total | 426,157,198 |
Key: prescription, prescribed drug, best selling
Source:
http://www.medscape.com/viewarticle/844317#vp_1
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